All depends if you're stable or not and if your max temps are ok (for me that equals low 70s max, cause its about guaranteed there's temp spikes you can't see and it could be throttling). I've had Pascal cards not crash until +165 core and had one crash at +144. That said, I've never seen one be ok with that high of a core OC (+185).
Quick test is to run Furmark & see if it makes it through the canned test. You'll usually get a crash there if its not stable.