NH-D15S will it fit?

If you're worried about whether it will fit or not, go with a different alternative. The case supports 160mm fans and the NH-D15S is 160mm with the fan installed. It would be safe to say that it will probably not fit, although I don't think it interferes with the first PCI-E slot.

A better alternative is the Scythe Fuma.

No, the cooler won't interfere with the first pcie slot. Cpu coolers are very careful not to intrude on that slot as it's where the gpu goes in 99.99% of all modern motherboards and ppl really do not like being forced to use the 2nd pcie, if the mobo even has one.

The only thing that large cpu coolers tend to do is overshadow the first ram slot. This isn't usually an issue, as you are really supposed to be running 2x sticks in slots 2/4 not 1/3. If running all 4 slots, you'd need short ram, not the tall heatsinks of some brands and series.

That's just odd. The NH-D15S is the same as a NH-D15 except that it only uses the 140mm center mounted fan. The regular tower has 2x 140mm fans. So how the center fan has clearance for the gpu and the front fan doesn't is beyond me considering they are the same fan, same mount, same tower size etc.

The D15 is basically king of big air, there's other towers that'll perform similar, Cryorig R1 ultimate, beQuiet dark rock pro 3 etc, but you'll run into he 160mm limit on all of them with a 140mm fan. You'll run into 2x choices, drop performance to 120mm fans like on the Cryorig H5 or use an AIO liquid cooler, some of the 240mm like the Swiftech H220-X or Fractal Design Celsius will be similar performance to he D15, or most of the 280mm will top it at maximum or match it at less than max.

Home Reviews Cases, Cooling & PSU CPU Air Coolers Noctua NH-D15S D-Style CPU Cooler Review By: Chad Sebring | CPU Air Coolers in Cases, Cooling & PSU | Posted: Aug 20, 2015 2:19 am Comment | Email to a Friend | Font Size: AA TweakTown Rating: 98%Manufacturer: Noctua Noctua NH-D15S CPU Cooler     While going by the fan direction, this would be the front, and we see that the fin count and shape is the same as in the D-15. However, when you look below the fins, you can see that the pipes are offset allowing more of the cooler to be shifted away from the PCI-e slot.       While we will eventually flip the fan from its stock location, we do see that the fan is supported with wire fan clips that lock in just before the fin supports are found on each tower. Also, since the fan now offers rubber corner pads, the Teflon strips are no longer used.     Technically this would be a front view of the cooler once it is installed properly on a motherboard, and it is much easier to see how the offset of the pipes running through the tower moves the D15S much further away from video cards.     On this side, we see more of the fin supports closing off the sides, and of course the fan is hanging there too. What we wanted to point out is that the 165mm is a hard minimum height with the fan, as we have it against the mounting screw now, and ours stands 166mm in height.     Looking at the top of the cooler, comparing this side by side to the D15, this new D15S keeps the same exact fin shape, and with the Noctua name readably oriented inside of the chassis, it is easy to tell the fan would be blowing the wrong way.

That's confusing. In one sentence, the heatpipes are supposedly offset to change the location of the towers away from the gpu, but the towers are still the same in the picture, you can see the base is still centered. And ppl have been using the D15 for years and I've never seen ppl having pcie issues, only ram slot issues. The only time I've seen any of the big air coolers interfere with gpus is when the gpu has a backplate that stands off the gpu too far. So unless vendors have shifted the 270 pcie closer to the socket (that'd be a stupid move) something is off. The D15 and D15S are the same heatsink, the S has just 1 fan, the D15 has 2 fans but both have capability for 3.

Why don't you just get a U14? It's very similar performance wise for sub 150W workloads and shouldn't have any clearance issues (check). The u14 actually handles overclocked threadripper CPUs decently well. It's a good cooler for the consumer platform.

Height without fan is 160mm, height with center fan minimum is 160mm, height with dual fans can be taller due to ram clearance of first slot. As is ram clearance on front fan is 35mm,so any ram taller than @33mm will require raising the fan, which can easily bump clearance to 165mm or more.
Personally I'm not fond of absolutely maximizing space above the board, case dimensions can and often are slightly off due to warps, windows, padding etc and can easily not be exact, leaving the cpu cooler touching the sides of the case, which can be an issue with scratching on windows etc.