Can gigabyte gab250mds3h motherboard support radeon 8 gb ddr5 graphics card

Solution
precise video card model please. ? as for the motherboard GA-B250M-DS3H should be able to handle all video cards (as long as you have the right power supply with it) right up to the 1080TI video card series. and later when new ones comes out
Does the board has PCI express?
Does the graphics card has PCI express?

If you've answered both questions with "yes", then it will work.
PCI express is compatible through all it's generations. Only rarely are there combinations that just refuse to run.