I wouldn't. If you want your CPU to have a LONG life, then I would not push any AMD or Intel CPU from the last fifteen years past 4.5Ghz on a permanent basis. Exactly as Photonboy has explained, you WILL degrade the CPU at a much faster rate than was intended by doing so. If you are stable and temperatures are within the acceptable envelope, then I would either stay where you are or even drop down to 4.5-4.6Ghz for the sake of longevity.