I believe so.
Not much point in doing so, but I recall Linus Tech Tips did a video on the very subject (using some hack to avoid needing the special dongle from Intel)
https://www.youtube.com/watch?v=lzzavO5a4OQ
Assuming you want to boot from it. If not you can set up a RAID drive via software or hardware I think.
Really you would only need that much drive performance if you are moving around truly massive files and had access to a 10Gbps network (or more)
I use a 1TB 960 Evo as my only drive and I have zero complaints over my old SATA III SSD raid setup.