I can't imagine a scenario where it would be worth putting a liquid cooler on such an old CPU. Anyways, a Be Quiet! Silent Loop 280 or Corsair H100 (not H100i) are good liquid coolers with LGA775 support.
I hope you do realize you can sell your QX9650 for $80 to $100 on eBay. Depending on the motherboard. You can likely get anywhere between $50 and $130 for your motherboard. Plus $10 to $20 for your RAM. Depending on how much you have.
If you add all that to the cost of a good 240+mm AIO liquid cooler. Let's say $120 to $150. You'll have a total budget of $260 to $400. In either instance you can get a modern CPU, motherboard and RAM. Which will dominate that QX9650. Even with a maximum overclock on the QX9650. A lowly Pentium G4560 will crush it on single core tasks and break even on multi-core.
If you wanted a new setup with liquid cooling. That budget could get you anywhere from a Pentium G4560 to a Ryzen 5 1400 (OC Capable). Either setup with 8GB RAM and a Corsair H60 liquid cooler. It's just a basic unit but they don't need anything like the QX9650 does. Comparing overclocks a Ryzen 5 1400 is up to 135% faster than the QX9650 in raw performance.
You also have to factor in the modern CPU will use a lot less power. The motherboards will support much newer standards (PCIe 3.0, USB 3/3.1, SATA III, M.2 NVMe, DDR4, Possibly USB 3.1 Gen2, UEFI). The CPU also support modern Instruction Set Extensions. Which will get far greater performance than the Core 2 on optimized software. Such as AES encryption.