The motherboard will boot at any standard 1.2v speed by default.
That may be 2122, 2400, or possibly 2666.
Once in the bios, you can select an XMP profile that will run the ram at a the ram higher advertised speed.
This is done by using setting profiles for voltage, cas and speed which is imbedded in the ram itself as xmp profiles.
All you do is select one of the available XMP profiles in the bios ram configuration settings.
Any ram specified at >2400/2600 speed must run at a higher than the standard 1.2v
Not to worry about the details, that is taken care of by the xmp profiles in the ram itself.