Not really. As long as the gpu stays within operating perameters, it'll last as long as it lasts. It's only when pushed beyond acceptable temps that deterioration and electrical bleed start ruining things.
Test the airflow. Test the game at a certain point, for @15mins, record the temps. Pull the side off the case and retest the same point for @15 mins recording those temps. In a case with good airflow, there'll be little difference in temps. If the gpu is starved for airflow, or has its exhaust returned, there'll be a sizable difference.
Just because a case has potential for good airflow and plenty of fans, doesn't necessarily mean it has good flow, just means it could.