Both CPUs are the same socket type so should be okay if BIOS supports Q6600, if it doesn't then hopefully your PC maker has released a BIOS update to make it compatible - - - best if you check the Acer website first or just risk it and buy a Q6600 to see if it works. Sorry can't be more certain but it's not easy to find CPU upgrade info for factory-built computers, you might want to contact Acer tech support and ask them.