Well yes, something could be broken or have developed a flaw. That is NOT to say you broke it - the unit has sat doing nothing for a while.
O suggest you follow a very systematic troubleshooting approach called Breadboarding. Look up the detail of how to do on Tom's website. I'll describe it briefly so you can grasp what the process does. Basically you remove everything from your case and assemble a bare-bones minimum set of components outside the case, mounted on a dry insulating surface to prevent short circuiting something on the bottom of the mobo. One type of material used for this was a dry clean wooden board, hence the name "breadboard". You try to start up[ the bare-bones set and see what happens. If that can't work as it should, you know there is a fault in that small set of components. But if it does work, you shut down and add ONE more component and try again. You keep up this process until a newly-added component causes failure, and then you know what is "bad".
VERY roughly, the sequence of components is:
1. Mobo with PSU connected, CPU and its cooler installed with cooling fan plugged into CPU_FAN header, ONE RAM module plugged into the proper slot for a single module. Your mobo has no on-board graphics chip, so without that you cannot display anything. IF you want to try a small step first you can power up this basic setup. All it MAY be able to do is start up to the extent or running the CPU fan and, after a short time doing its POST process, appear to stop and do nothing more. IF it has its own little mini-speaker or "beeper", it may sound out a series of beeps at that point. that's as far as this can get. To actually start it up, see your mobo manual on p. 2-35 regarding the System Panle Connector at lower right of the mobo. Note that near the middle of the bottom row are two pins labelled PWR and Ground. These are where the plug from the case's front panel POWER switch is plugged in. That switch is a very simple momentary-contact switch like a doorbell pushbutton. The case front button, when pushed, merely connects those two pins together when it is pushed. For your purposes here, you need a small screwdriver to simply short together those two pins for about a second, and that should start the system up. When you have finished whatever it can do, use the PSU power switch on the back of it to turn the entire system off. Then proceed to the next addition of a component, turn on the PSU rear switch, and short those two pins again to start.
2. The next component for your situation is the graphics card. Install it in its slot and connect it to your monitor. This time it should be able to show you stuff. Turn on the monitor first, then use the screwdriver to turn on the system. It should be able to go though the POST process and then halt with a message to insert a bootable disk, since it can't boot with no OS. If you get that, you have success and can go on to the next addition.
3. Next try adding one more RAM module. If you have more than two, add more in a separate test step.
4. Add the keyboard.
5. Add the mouse.
6. Add a hard drive. At this point it MAY be able to boot from that.
Keep on going until you get a failure. IF you can get ALL of the system to work outside the case, then you will have to suspect there is a significant problem with the way the system mounts in the case that causes it to fail.
As I said, that's a brief outline. I encourage you to look up more complete details of the breadboarding troubleshooting process on Tom's.