Perfectly possible.
4-X-4-8
4-8-4-X
8-4-X-4
X-4-8-4
Any of those will get you working as dual channel, as there's technically 8Gb in each, regardless of amount of DIMMs used. However, this comes with the understanding that all of the ram will run at the slowest speed and highest timings. So if that 1600 is Cas9 and the 1866 is Cas10, what you'll end up with is all the ram running at 1600 Cas9 (that's default speeds for DDR3, 1866MHz is an XMP setting). The only way to avoid that is manually OC the 1600 to 1866 (many will take that small OC bump) and leave all the ram now running at 1866MHz Cas10.
Warning: There is only One guarantee about mixing ram from different batches/kits, there are No guarantees it will work. The different ram may play nice or it may not. It may need a small voltage bump or not. It may need timings relaxing to Cas11 or Cas12 or not. Or it may work perfectly as is or not at all. I've had identical ram only 5 serial numbers different totally incompatible and had ram of different vendors, speeds, timings and voltages be perfect as is. Absolutely no way of knowing in advance. This is why it's always better to buy ram in a kit, it's factory tested for compatability, mixing ram you could swap the stick once or a hundred times to get it all working. So if it doesn't work, it's not that the ram is bad, it's just not compatible and won't play nice.