I'm not too sure but I think it may be possible. Sysprep is used to prepare a machine to be ghosted, as soon as you reboot after running that it'll do a redetection of hardware. So you may want to try using Sysprep, when it shuts down <b> DO NOT</b> power up again until the HW has been switched. I'm not too sure if it'll work that way but you can give it a shot. Be sure to post what happens, I'd like to know if that works.
i dont know if this works in 2000 but its good for win98se. just boot using a startup disc and reinstall windows. it doesnt overwrite any settings or data it just repairs windows basically. like i said i dont know if this works in 2000 as ive only ever tried it in win98. give it a shot if nothing else works