Wow, that is quite the system.
I'm not sure how fast your 8GB of RAM is, but since you have liquid cooing and a GTX 295 with 1,792MB mem., I will assume it is a major brand of DDR3, probably Corsair or Mushkin, since they are the only brands they seem to be capable of handling the speeds and heat.
As long as you have the latest patches and drivers your system should have no problem rendering that game on high settings.