I have a ASUS A7V333 mobo a AMD XP 1700 right now with a 1Gb of RAM. I have no probs installing Redhat 8 or upgrading to 9. I haven't get a clue as to what Mobo your looking at and cpu. Really shouldn't matter to Linux in the least. Just make sure you have a compadible graphics card and if you want sound make sure you have a compadible sound card. I have an Audigy Gamer and Redhat won't see it. Samething goes for your Modem or NIC. I can't speak for the newer mobo's out there. I haven't had 1 prob in the least and Redhat screams with all the RAM I gave it.