Eve on Mac doesn't run natively, but on top of Cider (the win32 implementation for Mac), which eats some of the performance. A comparable Windows PC would therefore run it a bit faster.
I haven't tried running Eve in high resolutions. But I think the 3D lag depends mostly on what you display on screen any given moment. When I tried high settings on my current system - it's actually another MB Pro maybe 4 tiers below your specified system, looking at http://www.tomshardware.com/reviews/graphics-card-geforce-radeon,2646-7.html
for example - undocking from a station made the game a horrible slideshow, because the station model etc. were displayed. Once you zoom out it gets much better. I suppose lots of objects on the screen, even zoomed out can hurt a little bit, so if you want fleet fights you may need a bit more performance.
Your specified CPU is quite powerful, and RAM is plenty. Eve is quite light as games go - I recall wondering at the client size of 256MB back in the day when HW2 for example was over 1GB at times... If you really want eye candy in your Eve you could consider putting more money into the 3D card.
My wild guess is that you'd manage it at least to medium with that spec. But it depends quite a bit on what you do in Eve and what you consider smooth.