Crysis 2 locks up my computer

[IDrill]

I have the same problem. I am running on 2 video cards (Crossfire)

 

[Gman450]

Tried the latest patches from Crytek ?

http://games.softpedia.com/get/Patch/Crysis-2-Patch.shtml

Are your graphics drivers up to date ? If problem still persists, then disable crossfire.