Moving mouse causes fps to drop to 0

Hi guys, i have searched for weeks with out finding a viable fix.

So here is the thing: When playing certain games after a few minutes the mouse starts to lag. Not a stutter or anything, but complete drop to 0 fps. When i move with WASD i get absolutely no lag, i can spin around and have no lag at all. But if i move the mouse, it drops to 0 until i stop moving it. The weird thing is, it doesn't do it with all games. While playing MW3 it happens and if i move my mouse the FPS drops to 0, but it stays hi using WASD. I can exit out and go play Minecraft and it does the same thing. But, if i go open Skyrim, it does not have this problem.

Specs:

GPU: GTX 275 896mb
Processor: Intel 2 Core Quad CPU Q8300 @2.5GHz
Ram: 2x2GB DDR2


The only way to fix this problem is to restart the computer. Though it starts acting up awhile later. This is not a virus because I recently reformatted my computer, and I had this problem before I reformatted.

PLEASE HELP,
Corey