I have never seen any serious improvements with registry cleaners... they pretty much seem like a joke to me. Even after having an OS install for about 2 years and having tons of uninstalls and installs of crap a registry cleaner hardly made any difference worth mention. BUT just my 2 cents.... agreeing with Jonmor68 on this.
Agreed, there is no such thing a good registry cleaner or optimizer.
Leave your registry alone. It does not need cleaned or optimized in any way, shape or form. It's just BS software written that most likely going to install more spyware and adware on your system when you download it, and end up causing more problems than it will ever cure or fix. People who actually pay for these programs, well like they say, a fool is born every minute.