Go to Add/Remove programs and uninstall it. But something here does not make sense, your post title states hard drive, your post states DVD drive, which is it? The drive would have come with a manual that explains the program and how to use or remove it.
Thanks for the reply. When I loaded EZ Transfer, the program installed itself on the E drive which happened to be my CD ROM drive. I found the solution. I just went into MY COMPUTER and renamed the CD ROM drive to F. Everything works fine now.