Are PSU units universal?

I need to replace the crappy 250w factory one and I was looking at the epower puma II,but I want to know if any problems can occur when I replace it. I recall somewhere that some mbs could be damaged if an incorrect power supply is used. It has an Asus K8S-LA mb(754 socket),SIS 760GX chipset.Thanks
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  1. I think i replaced at least 5 PSU's in my life and i never had any problems, :D
  2. Thats's good to hear. I ordered a 6800GS to replace the integrated video and seen that I needed to upgrade my psu.
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