Funny, My E M T6412 came with a 20 pin Bestec PSU connected to an MSI Xpress200 (M420-IL) 24 pin mobo, and when I connected the newer PSU I thought "What The Hell?" How did they get away with this? No wonder my machine is rebooting!!
That was until I went to the MSI website and downloaded a copy of the motherboard manual. It says that connecting the 20 pin to the 24 pin is OK. I went wit an upgrade because I could see tha 'OK' for everyday Joe @ the office who's PC sits on for years and they only do spreadsheets,
but if you pull MAJOR power from your PC running the latest and greatest boards and stuffing the bays to the max and loading every slot,
Yep, you are for sure going to need that 24 pin deal PSU because your going to need 'all lines open' to deliver the power needed to run that mammoth monster you've created.
Hope that answers a question.