Or if you have unlimited budget and want to go absoultely wild on it try this(similar to my setup):
-2x73GB Maxtor Atlas 15K II
-4x300GB 7200RPM SATA in RAID5
This implies that you have an unlimited budget. Please send me a dozen Opteron 175s, a dozen 165s, a plethora of DFI mobos, a truckload of Thermaltake cases and watercooling toys, a railcar full of Raptors, a box full of fast OCZ memory and a pallet of high end PSs. Thanks! I'll mention you in my autobiography.