I've got 3 machines running w/ Epox boards and I've never had a single issue.
I haven't used this specific one you're asking about, but I just built an AM2 system with the MF570SLI board and it works as advertised with no issues.
The 570 also has a windows based flash utility which makes updating the bios real simple. The only thing it doesn't have is firewire on the back panel (???) though there is a header for it if you want to add a PCI card.
I'm just learning to OC so I can't give you any whiz kid answers about Epox capability vs. DFI etc. So far it seems pretty OC friendly, though I will say that the bios using a little different terminology in the memory settings which means I'm doing some guessing when comparing it to all the stickies and guides I've found.