Triple monitor gaming in windows7 64

Are there any tricks to running games well on a three monitor setup?

I only have 2 x16 slots running dual evga 275 gtx oc on a tyan s2915 motherboard with 16 gb ram, dual quad core 2356s,raid x-25m ssds and three 24 in monitors under windows 7U 64. This is loads better than vista 64 (I can't even talk about it) but it still chokes when the action gets heavy. Obviously this computer is used for manuscript creation-writing model analysis by day but I like to have a little fun at night. Hence I would like to tweak what I can without going to two monitors (can't stand the line in the middle) or going to a new MB.