the manufactures website should have the various drivers availible for download.
How do you know its the drivers ?
Check USB configuration in BIOS.
Your USB device's should be detected in some way even if they don't work.
Are you plugging the device's into the USB connectors on the back, Because if you have a case that has USB connectors in the front there's Gaurantee that their actually plugged int anything.
Also what OS are you using ? probably best supply some details about your setup if you wish for a speedy resolution.
Make sure USB isn't disabled in device manager or something wierd like that.