Quadro's are workstation-class cards, there the user is not greatly concerned with high frame rates (such as shooter type games) but needs high precision. How much AutoCAD do you do, how big is your screen, and at what resolution? This application is very different from games so the percentage of time you spend in each will make a difference in the card you choose.
The PNY will work for you just fine if you mostly focus on AutoCAD. But if that is 30% or less of your computing hours you should probably look at other cards.
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