What a dumb question - which is better: Rosetta or Folding?
They both go for calcs on protein folding (if I'm not mistaken) - so what the fcuk does it matter who's better? I mean, in theory they both use the same calcs - it's the distributed system that yields the answer in terms of performance and in that case, the biggest one should be the "better" one.
Even if the calcs aren't the same, not knowing the differences is where the question ends. Also, with different methodology..... bla bla bla. I lost interest in addition to my super laptop allowing me to reply before I finished typing.
Message edited by Vokofpolisiekar on 06-19-2008 at 04:05:33 PM
I would say folding@home,it's easy to use,easy to change,and is relatively simple to use - Except for the GPU client...Never heard of "rosetta@home" though *googles* meh,nothing really exciting.
I think this site must be full of ignorant people who have a need to be tough on the internet because of personal problems or failures..
Those two projects both study proteins, but they tackle the problem in two different ways:
while folding@home tries to determine the 3d structure of a protein, starting from it's amino-acid structure, moddeling how the folding occures millisecond by millisecond, which is very very tough from a calculus point of view, rosetta@home as well tries to determine this 3d structure starting from the aminoacid chain, but it randomly generates millions of shapes it can assume, and by evaluating the energy that would be necessary for it to assume that shape it can determine which one is the correct shape (lower the energy more similar it is to reality)
i hope you found some help in this reply, i personally run rosetta@home, so if you have any questions regarding it don't esitate to ask!