Nice motherboard.
I love mine.
You won't have to do any hardware mods. 3.0 should be an absolute breeze. I can OC my xbx2 and 6600 to 3.2gz w/o adjusting anything but the FSB speed. All CPUs are different, so you experience may be better or worse than mine.
First off, read the C2D OC guide stickied to the top of the CPU forum. It'll give you a feel for how things work. After you've done that, read the rest of this...
So... to get your fsb:ram to 1:1 you'll need to enter the "Memory Configuration" section in the bios. Move the Memory Frequency to 533.
Then go to the "Processor Overrides" section and move the FSB Frequency Override from "Auto" to "Manual". This'll open up the "FSB Frequency" option. You'll probably get at least 3.0ghz stable w/o adjusting your vcore... so try that. Move the "FSB Frequency" to 333. This will overclock you to 2.997ghz.
Now run "Stress Prime" to test stability. A good first test is like 10-15 minutes. A true test is much longer.... like overnight. But don't bother with that until you feel you've reached the edge of your overclock. You can download Orthos ("Stress Prime") from www.techpowerup.com. If you're stable after 10-15 minutes jump back in and up the speed a bit. I'd try 356 FSB (3.2ghz) next. (This is the point at which I need to add vcore.) When you do fail orthos you know you need to play with voltage. You'll know when it happens. Orthos will flash and beep, and generally b*tch at you.
Move the "CPU Voltage Override" in the "Processor Overrides" section up one notch and retest.
Note: The first time you move the "CPU Voltage Override" off of "Auto" make note of the "Current Processor Voltage" beforehand. You'll want to set it one notch above that value. The default will be lower than that value.
Be sure to post your results! Good luck.