This is actually quite easy. Any decent modern video card will have two video outputs. (Not three outputs- the only card I know of that supports 4 is a Nvidia Quadro; and they cost mucho dinero) Hook the Primary and secondary monitors up to your best video card. Easy.
As for the third and fourth cards, this is a little more tricky.
Is your system AGP or PCI Express? (I will assume PCIx because you mentioned SLi)
What do you plan to do with these displays? What resolutions are these displays?
If you plan to run web pages or something not demanding on a low resolution, you could just buy an older PCI (Not Express) card for really really cheap and run them on this. If the resolution is higher, or you plan to game, etc., you should invest in a higher end PCIx card.
As for SLi, it will NOT run more than 2 monitors at a time. Just FYI.
Best of Luck