I personally love the P180,
For cable wiring it actually forced me to do a better job.
you can force a 6-pin modular ps cable in the little corner that separates the lower hds from the ps. which gets rid of the power cable woes going them. and stick your sata cables out the back through a small hole just at the back of where the 4-disk brick slides in. it maybe stricky to slide it in the first time but once you have done that you have no problems with the lower part of the case.
As for the upper section you can use the cable shroudy jig to make a much neater section for the cables to come out of the bottom if you push them through the correct sections..ie use only the power cables that require to go in the top through there.
for the 4-pin 12v cable that goes all the way up to the top of the board, you can actually run it underneath the graphics cards and it is complely out of the way. i have mine run between the top pcie slot and the chipset fan then alone the pcie slot and put the molex cable in and continue up to plug the 12v 4pin one in...after that u only need to connect the power to gfx cards which you can do on the same cable line as the molex pcie power and 12v 4pin plug. and if you use zip ties you can make it seem as if there is almost only 1 cable running through the case.
once you have finished it fits perfectly and you have only the ATX cable and the power to the gfx/pcie/12v4pin all running under one wire length.. its very neat.. but can be cramped, especially if you power supply has particularly stiff cables.
if you are using ide cables for the hdd then stick it in the external floppy drive section and fold the ribbon cable at 90degree angles a couple of times so that most of it goes under the board then when the cable meets the ide port just let it come out and fold around to plug in.. (make sure you have the right orientation for the final fold otherwie youll be pissed and have to refold a folded cable and makes it a bitch, not to mention the possibility of impeding the cables quality if you fold it too many times(ie wire brakages))
with this wiring scheme i can have a fairly neat wiring job that house.
a A64x2 w/ bigtypoon, 4gbram, 2x6800gs in sli 4x250gbs hds, a dvd, and a primary system disk and barely any wires in the way at all. One small note, if you use zip ties and your cabling is neat and TIGHT, then removing graphics cards can become a real pain because it would be zip ties to tightly to the other cables going further up the board that it is almost impossible to get out of the gfx card..
if you want another case with similar sleek looks id go for the Thermaltake matrix. although its a bit smaller its a good case for neat computer use.. has these funky little screwless hdd and dvd drive install things and you need no screws to install any cards..
also its thrumb screws are very big and easy to use buit you can leave them off and just use its locking mechanism instead. but as i said its a much smaller case.. yet youd be supprised by the amound of space inside..
oh yeah another thing.. the antec p180 without a computer in it is about as heavy as say a mtrix wiith one in it.. and you can imagine the weight when its loaded..