It would definitely work with one stick, but two is preferable. With two you would have dual channel memory.
What is your processor? That makes a difference on the speed of the memory necessary.
my processor is a pentium 4 ...2.6 Ghz....and i have the OZC stick....my boss gave to me.....along with computer im trying to get it to run in.....he says it originally came out of that computer so it must work....and i got im to test it last night on another comp....so i know it works......ITS CRAZY