Mouse problems

Dont realy know which section this belongs too, but ill explain the problem here and people can either direct me to the proper section or try to help

Well for a while now, i do not have mouse functionality after my windows X64 starts and all loading is done, i can move the mose and such my buttons wont interact with windows and start menu, however if i CTRL,ALT,DEL and then just closes the taskmanager again (without doing anything) my mouse works fine.

The reason why its been like this for a while, is that first i thought it to be a hardware failure (Mouse not working properly), but lately and some debuging, have let me to beleve that its caused by some sort of software. or conflict, however, so what im hoping is that anyone in here have had similar problems and can give som hints to what caused it to make it easyer for me to debug the software i have installed.

/ps -- Sorry for my english.

Thank you, ill give that a shot, or a totaly new install