If it HAS to be CS3 then no you can not run it natively under Linux and WINE support is just not there yet. I'm sure others will point to the GIMP as a replacement application that does run under linux and also under windows so you could try it and see if it will allow you to do what you need to do.
As the web is supposed to be just a set of open standards isn't it sad that you find yourslef in that position. Thought for the day - Is adobe actually just doing the same thing MS has done with closed standards?
If you have a decent Dual core, you could run vmware or Qemu. I find it quite snappy with my dual core laptop has virtualizing instructions in the cpu. I use Qemu every day running XP at work, 3d apps do not run terribly fast, but 2d apps run just like everything else.
The new CPU's make it feel just like a regular session.