Adobe Photoshop® Extended and Acrobat® Pro natively support 64-bit editions of Windows Vista. Adobe Premiere® Pro, After Effects®, Soundbooth®, Encore®, and Adobe OnLocation™ are certified on 64-bit Windows Vista.
http://www.adobe.com/products/crea [...] ystemreqs/
To put things in perspective, this is what 64-bit does...
What are the advantages of 64-bit computing?
In early testing of 64-bit support in Photoshop for Windows®, overall performance gains ranged from 8% to 12%. Those who work with extremely large files may realize noticeably greater gains in performance, in some cases as dramatic as ten times the previous speed. This is because 64-bit applications can address larger amounts of memory and thus result in less file swapping — one of the biggest factors that can affect data processing speed.
http://www.adobe.com/products/phot [...] moid=DRHXB
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