I have just bought the Medusa 5.1 Home Edition - I use it for games (2142 and Stalker at mo) and it is very comfortable when wearing for long periods. However, it does suffer from a very annoying flaw - in that the centre speaker lacks bass.
Anything in front sounds odd and ruins the 3d nature of certain things at certain times. But it is not often that you can't see something right in front -a lot of others have described similar problems in the rear.
If you are prepared that they might not be perfect - they aren't a bad choice. But I am not sure if I have the damn set up correctly - so the error might lie with my own lack of knowledge.