application configuration incorrect - help please!!

Not sure exactly which subsection this should/could go, so appologies if it is incorrect,


source: http://www.abload.de/img/mumble5ci.jpg

i am having problems opening that application in the above screenshot "mumble" - it works fine downstairs on another system with XP 32bit, and it worked fine on this system with Vista 32bit, however after conflicts with vista and my gfx card swapping 2d/3d every 2minutes in cpu intensive games with the current drivers, i have formatted xp back on, all programs and apps are working fine except this one (even this installed ok, i just cant start it up) - even on reinstall

if you dont know what mumble is then its a free voice communication software for gamers with <2ms inbuilt delay

thanks, driving down to overclockers.co.uk now to pick up some new ram, hopefully someone will know the problem so i can rectify it when im back, lots of love and appreciation n advance!