I really don't use anything special Office 2007 alot, Nero 9 ultimate, Adobe Acrobat 9 Pro alot, heavy Email in Outlook and Firefox for 97% Internet. Acronis TI2009 for daily images, as this is a work from home business computer. Most of my work is in Acrobat, Email and Word, between those 3 its about 85% of my work, the rest is burning and acrhiving CD's and DVD's (I'm on my 3rd burner as I burn numerous times daily)
I really am fine where I am since Vista SP1, When it came out I did a complete clean reinstall and the computer worked so much better than it did when I first got it and still is working really well. I just hear about alot of people going '64' I thought I would look into it since I had the ability to do so.