For memory configurations 1GB or higher, ReadyBoost does not improve system performance, at least not enough for you to notice it.
So there you have it. ReadyBoost can slightly improve performance for users with minimal amounts of system RAM, particularly when it comes to application and boot time.
If you've got an older system and find Microsoft Windows Vista a bit slow, ReadyBoost can act as a band aid solution... but I think in the long term you would be much better served by upgrading to at least 1GB of system RAM.
On the other end of the spectrum, if you have a fairly current computer system, ReadyBoost seems to have little to no effect at the moment.
Apologies if this topic has been covered by a Tom's Hardware article or forum topic.
The article sounds accurate enough to me. I enabled it on my thumb drive when I had only 1 gig and noticed nothing. In fact, even when I added another gig or real RAM I didn't really notice a difference.
I'm sure it was only intended for what the article suggests, a band aid.