What rubbish is that? "Also as most artistic designers are left handed" Don't think you're so special. Majority are ACTUALLY right handed.
It would work. Give all the details of your problems. Because I had a genius graphics tablet and it's all the 64-bit apps that now accept whereas they never used to with XP -
Also - what Operating system are you using? If you expect 64-bit apps to work on normal XP or whatever you're using - the x86 systems.. you need to go read a bit..