If I understand you correctly you want to save your programs like MS Word etc; then no you can't do it.
You can save the files created by these programs, but the programs will need to be reinstalled from the instalation media.
If you have a proper Microsoft instalation disk (not a manufacturers restore disk) reinstaling Windows by booting with the windows disk will put the previous instalation in a folder called Windows.old providing you DO NOT format the drive.
After instalation is complete you can access this folder to recover your data files such as documents, photos, music etc.
You can delete this folder once you get what you need out of it.