Windows cannot load the device driver for this hardware. The driver may be corrupted or missing. (Code 39)

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Troubleshoot fails to fix problem, ASUS DVD-E616A3T went to the asus website and downloaded the newest firmware, failed... when I first booted up my computer it worked perfectly, but my graphics card wasn't being registered so i went into bios and fooled around with the IRQ settings, that's the only thing that I"ve done and the drive suddenly stopped working, any help? I don't know how to apply the firmway any other way then by device manager update driver and locating file, when I do it says "best driver etc etc etc" Conflicting messages.