From what I read (as I'm migrating to WC), phreejak gave a good answer: The MCP355 is the best pump for 3/8 tubing, as it has a much better head than the MCP655. But, as its flow rate is smaller, it will be more suited for short loops: one WB + Radiator.
The real questions are:
- what are you willing to cool, what components you use
- why going with 3/8 tubing? 1/2 tubing will give you more upgrade options for later. Also, you can use 7/16 (hard to find) tubing: same great flow rate as 1/2 but less bulky
Also, better go with the MCP355 with petra's top, as it will give you a much improved flow in the circuit
I'm not a pro, but read much about it recently. others could correct me if I'm wrong