Usb internal drive on my desktop stop working

I have usb drive on my desk top 2 in the front and 4 in the back only one in the back is working for my printer when I plug up my mouse it does not recognize my mouse I tried other plug mouse please help
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More about internal drive desktop stop working
  1. Plug in your devices.

    Start-->control panel-->system-->device manager-->drop down USB devices-->right click and uninstall all of the USB root hubs-->restart.

    They will reinstall on restart, and look for new hardware.
  2. Is that mouse is working on other system?
    have you tried plugging in that printer to any other USB ports??
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