Several of the "Professional graphics" or "workstation" video cards" are the same as the ones you might be more familiar with. The difference is in the BIOS and the drivers. For animation and design, the 8800 GTS would be plenty for you. It's optimized for open gl as well as all the other stuff. I was quite shocked when I read reviews for some of the professional graphics cards. Repackaged, with a new name, BIOS, and drivers and supposedly you have a totally different card, for a much higher price I will add. It's different if a card is optimized for certain apps, or for certain functions. Take a look at the specs between the GTS and the "professional graphics" card you want. The GTS accelerates everything well.