I have this board, running an e2180. I have the setup at 10x multiplier, 300 bus speed. Im also using the 2.5 option for the 750 mhz bus speed. I tried to up it to 3, for a 900 bus speed, but I keep getting BSOD's in windows. Im pretty happy right now with the 3 ghz, which is what I wanted out of this chip. I believe im at 1.392V according to CPU-z. I may try to bring that down some, but its still not too high. I have the ram running at +.4 v, which should be right at its rated 2.2volts, since the board defaults at 1.8. I have the PCI express set up at 100. I just built this setup yesterday, and everything went well the first time.
I clean installed using an upgrade disk from vista ultimate. Im getting 5.6 in vista's experience thingy, which is the processor's speed. Everything else is a 5.9
E2180 3ghz (300x10)
EvGA 8800GTS Superclocked
Seagate 7200.10 250gb
2gb Crucial Ballistix 800mhz