You can't OC a HDD. You could try firmware mods but that's pretty much all you can do to a HDD. If lokking for a blazing fast HDD look at the Seagate 15k RPM drives or the new VelociRaptor.
That is hilarious! Yes, overclock the HDD from 7200 to 10k, just like the Raptors, only cheaper! Don't waste your money on that stock 10k, just take out the ground wire from your molex connector and add an additional 12v! Should get you to 10k, easy!
Most 7200rpm drives perform about the same... 10k drives are a bit faster, particularly the new WD velociraptor. SSD's are the fastest, but very pricey. Go to storagereview.com http://www.storagereview.com/php/b [...] h_sort.php and pick your workload for a good comparison. Synthetic benchmarks like hdtach do not tell a realistic story.
---------------
E8400-stock, GA-P35-DS3R(rev2.1), Corsair 4x2gb 6400C5, EVGA 8800GTS-512-G92, Vista home premium-64-bit, WD velociraptor-300gb, PC P&C silencer-610, Antec SOLO, 2 x Samsung 275T, Samsung-203b-dvd
If speed is of utmost importance, go for a 10K RPM WD Raptor/VelociRaptor. Otherwise, if you're interested in the 500GB-750GB range (like the one you linked to above), then you've already pointed out a good choice.