Not really. Most mobo max out between 450-525 fsb with a quad core processor.
q9450
450 x 8 = 3.6ghz
525 x 8 = 4.2ghz
q6600
400 x 9 = 3.6ghz
500 x 9 = 4.5ghz
Of course I realize that temp and voltage will prevent all but the "golden" q6600 chips from reaching 4.5ghz, but it has been done before on air. A good q6600 will still get 4ghz on air and a bad one will max around 3.6ghz.
The point is that unless you know your motherboard is going to do smoking fast FSB speeds the q9450 isn't worth the price hike.