Will the new 45nm cpus work with the 680i LT SLI?

The Dual-Core 45nm will work. (E8000)
The Quads will most likely not.

zen beat me to it...mind you it is still a possibility...

as to your question....are you overclocking and....how much money are you going to spend?

This is the setup i am thinking of getting:
XFX nForce 680i LT SLI Motherboard (Already have)
XFX 8800 GT Extreme Alpha Dog Edition 512 mb 640/1900 (Already have)
Western Digital 320 gb 16 mb HardDrive
OCZ Gold Revision Dual Channel Kit 2gb RaM (already have)
Acer X203Wbd Black 20" 5ms DVI Widescreen LCD Monitor
ZALMAN CNPS9500 LED 92mm 2 Ball CPU Cooler
Creative Labs Sound Blaster X-Fi XtremeGamer Sound Card

Well this is going to be my 1st time overclocking so i will be overclocking.

Should i wait for the 45nm e8000 dual cores or just get the Q6600 now?