I want to let everyone know who plans on buying a Core 2 Duo 45nm. The Asus P5N32-E SLI will never ever support 45nm Core 2 Duo. I have talked to ASUS tech support, and they are never going to release a BIOS that will run the e8400 and e8500 at full power(it underclocks it stock). As far as the 45nm quad core, I know it will run a Core 2 Extreme, but I am not sure about q9450 or q9550. So now I am stuck using my old Evga 680i LT, which runs it perfect with no Bios flash.