P5B-VM does not has the RAID option the P5B-VM-DO offers if you are looking at the 965G chipset. The 965G support some of the 65nm Quad cores, but not 45nm processors. These micro boards have little in the way of the overclocking ability a full P965 board offers if that's what you want. I assume the G33 chipset may support Wolfdale as well as some quad cores, but again micro boards normally do not offer the overclocking ability of the full atx boards. The 965G is an older chipset than the G33 if that helps. Also, ASUS MB's have the American megatrends BIOS while MSI has AWARD Bios. I believe. User preference.
This would be a better choice thann the P5B-VM-DO which I have.http://www.newegg.com/Product/Product.aspx?Item=N82E16813131237